జర్నల్ ఆఫ్ క్లినికల్ కేస్ రిపోర్ట్స్

Case Report: A 40 year-old Male with Fever and Syncope

Abstract

Austin R Dosch, Lucero T and Everett T

Class I Brugada Syndrome is a disorder characterized by heterogenous, inheritable cardiac ion channel defects . It is believed to account for 4% of all incidences of Sudden Cardiac Death (SCD) and up to 20% of cases of SCD in which there is an absence of structural cardiac defects. Traditional findings on EKG are the classic “sail” appearance of the QRS complex and ST segments in the right pre-cordial leads, characterized by ST segment and J-point elevation without a distinct R-wave which down-slopes into an inverted T-wave . Patients often do not experience a syncopal episode until the 4th decade of life. Syncope is many times precipitated by a stressor such metabolic derangement or fever. The patient examined in this clinical case report showed a history of febrile illness along with syncope , with subsequent EKG revealing a classic presentation of this rare disease. Further work remains to elucidate the influence of high temperature and metabolic derangements on the development of symptomatic Brugada syndrome and how to best risk stratify these patients.