Raghda Ghonimy Elsheikh, Mohamed Salah Hegab, Mai Mohamed Salama, Mohamed Elsayed Elseteha and Amany Ibraheem Omar
Objective: To compare clinical and echocardiographic data before and after transcatheter closure of patent ductusarteriosus (PDA) with occluder device.
Methods: The study population consisted of 30 children with PDA who were subjected to history taking and clinical examination to detect symptoms and signs suggestive of significant shunting. Doppler, two-dimensional echocardiography studies with measurement of mitral inflow velocities in early and late diastole (E and A wave), early and late diastolic mitral annular velocity (É and Á) by DTI, Tei index, and standard chamber dimensions. All children were studied before and 3 months after percutaneous closure of PDA that done using the Amplatzer device.
Results: Transcatheter closure of PDA produced marked improvement of patients’ symptoms and signs postclosure, significant reduction in heart rate and respiratory rate while there was no significant change in blood pressure or temperature. Also there was significant reduction in LV systolic and diastolic dimensions and volumes, LV ejection fraction, left atrial diameter, E wave, A wave, É wave and Á wave while there was significant increase in LV Tei index and no significant change in aortic root diameter, E/A or E/É. Conclusion: Haemodynamic effects of PDA and changes in LV dimensions and function caused by it are reversible after transcatheter closure of PDA.
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