Kanjana M, Kanimozhi G, Udayakumar R and Panneerselvam A
The present investigation was designed to screen the phytochemical constituents of ethyl acetate extracts of endophytic fungi Chaetomium globosum, Cladosporium tenuissimum and Penicillium janthinellum were isolated from the medicinal plants Passiflora foetida, Memecylon edule and Justicia adhatoda respectively. The ethyl acetate extracts were prepared from endophytic fungi and the extracts were subjected to phytochemical analysis by GC-MS. In this study, the mass spectrum of the compounds found in extracts of endophytic fungi was matched with the WILEY8 library and National Institute of Standards and Technology (NIST14) library. The GC-MS analysis of endophytic fungi revealed that the presence of thirty three phytocompounds in Chaetomium globosum, thirty four phytocompounds in Cladosporium tenuissimum and thirty nine phytocompounds in Penicillium janthinellum including the antioxidant and antimicrobial compounds. The major chemical constituents present in the ethyl acetate extracts of endophytic fungi Chaetomium globosum, Cladosporium tenuissimum and Penicillium janthinellum such as 2-Cyclohexen-1-one, 2-methyl-5-(1- methylethenyl)- (13.50%), Bis (2-ethylhexyl) phthalate (12.22%), 2-Propenal, 3-phenyl- (9.39%), n-Hexadecanoic acid (9.35%), N-Didehydrohexacarboxyl-2,4,5-trimethylpiperazine (8.47%), Tetracontane (8.32%), 9,12-Octadecadienoic acid (Z,Z)- (11.97%), 9-Octadecenoic acid, (E)- (10.69%) and (1H-Benzoimidazol-2-yl)-[4-(4-methyl-piperazin-1-yl)- phenyl]-amine (8.62%). So, the present study confirmed that the presence of biologically active compounds in endophytic fungi of medicinal plants, which are used in the traditional system of medicine to treat many diseases. Further study is needed to isolate and characterize the bioactive compounds responsible for therapeutic values.
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