Utpal Bhadra
Disease therapy based on genetic materials is now a reality. The technique of gene silencing also called as RNA interference (RNAi) keeps our hopes alive. RNAi based drugs have now advanced steps closer towards clinical trials. The powerful in-vivo RNAi machinery and its delicate factors apprehend that RNAi-dependent therapies might create a billion dollar business against the pathogenic organisms and diseases for which treatment options are currently restricted conventionally. Recent years have highlighted both the promises and challenges in the delivery of different RNAi therapeutics. Apart from the delivery, the design, stability and degradation of RNAi based effective molecules appear to be the major lime light to challenge the conventional drug safety concerns and ensures to be the most powerful gene recovery in future which may execute a billion dollar business hope.
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