Vladimir V Kalinin, Anna A Zemlyanaya, Elena V Zheleznova and Lyudmila V Sokolova
The current study has been carried out in order to evaluate the possible relationship between premorbid personality constructs with therapeutic remission and seizures reduction under antiepileptic treatment in patients with partial forms of epilepsy. One hundred and three patients were included into study. There were 33 men and 70 women. The Munich Personality Test and Toronto Alexithymia Scale (TAS-26) have been used for the assessment of premorbid personality in patients. Product moment correlation and multiple forward stepwise regression were used for the analysis of interrelationship between independent variables (personality constructs) and dependent variables of therapeutic remission and percentage in seizures reduction. Obtained results have shown the favorable prognostic significance of Neuroticism, Extraversion, Frustration Tolerance for the percentage of sum of all partial seizures reduction and for sensory partial and motor partial seizures reduction. On the other hand, alexithymia correlated negatively with length of remission and percentage of all seizures reduction.
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