Mansour M, Souissi W, Beyrouti R and Mrissa R
POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. Polyneuropathy is the most common initial symptom and it can hide other features of this disorder. We describe a patient with chronic inflammatory demyelinating polyneuropathy (CIDP) associated with extra-neurologic signs fulfilling the diagnosis criteria of POEMS syndrome to emphasize the importance of meticulous physical examination leading to challenging diagnosis.
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