Zhang L and Wang P
Pyoderma Gangrenosum (PG) is an ulcerating, idiopathic, neutrophilic, non-infective inflammatory disease that primarily affects the skin. Pulmonary manifestations are uncommon. The most important differential diagnoses are pneumonia, lung cancer, lung abscess, and Wegener’s granulomatosis. Here, we present a case with fever, cough, and cutaneous lesion, which was initially misdiagnosed as pneumonia. A CT scan showed irregular cavitated consolidation in both lower lungs. Histopathological skin findings were non-specific. The skin and lung lesions rapidly improved with corticosteroid treatment. This case demonstrates the challenges in the diagnosis of PG with lung involvement.
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