Wael Ahmad Abu Dayyih*
Due to their ability to modify signalling pathways by binding to phospho-writers, erasers, and readers like proteins with SH2 and PTB domains, phosphotyrosine-containing compounds are the focus of considerable research. In order to research protein phosphorylation and dephosphorylation, phosphotyrosine derivatives are helpful chemical tools. As a result, they are appealing starting points for the creation of binding ligands, chemical probes to study biology, and inhibitor and degrader drug design. Physiologically stable phosphonate-based phosphotyrosine analogues are useful in a wide range of applications to overcome the enzymatic lability of the phosphate group.
ఈ కథనాన్ని భాగస్వామ్యం చేయండి
English 
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 