జీవక్రియ: ఓపెన్ యాక్సెస్

The Application of Metabolomics in the Development of Novel Diagnostic and Therapeutic Tools for Breast Cancer

Abstract

Lemus R, Vega A and Pérez-Estrada R

Breast cancer (BC) is widely studied due to its importance in the world public health. Currently, there are multiple standardized methods for its diagnosis including physical and molecular ones. The strategies for BC treatment are diverse; despite the availability of different therapeutic options, BC still remains one of the leading causes of cancer death in women. There is a need for novel diagnostic and therapeutic tools, and metabolomics approach could help us to develop them and to improve the already existing ones, which leads us to the possibility of a personalized treatment with reduced adverse effects and a better clinical outcome. Herein, we describe the targets that are currently being used in the diagnosis and treatment of BC and review the development of new ones based on metabolic alterations on BC. We conclude that a recent metabolomics approach can be a novel tool to improve the diagnosis of BC as well as constitute the basis for identification of new therapeutic targets.