Trishagni Talukdar, Ahmad Zahid
Uterine leiomyomas, commonly called fibroids are benign tumours of uterine myometrium composed of smooth muscle with variable amount of connective tissue. It is the commonest tumour of the female pelvic organ. 1. As it is vascular tumour, many a times Myomectomy leads severe intraoperative blood loss. It is estimated that the average volume of blood loss during abdominal myomectomy ranges between 200 – 400 ml, 2,3,4 with blood loss greater than 1000 ml considered as major blood loss.5 Vasopressin is a synthetic analogue of the anti-diuretic hormone, has a V1 receptor agonistic action thereby causes vasoconstriction . Intramyometrial injection of vasopressin helps to reduce significant intraoperative blood loss. However, it is not devoid of side effects and sometimes might cause very serious complications like arrhythmias, bradycardia, pulmonary oedema, and cardiac arrest. Here we are presenting a case report of sudden severe bradycardia caused by intramyoma diluted vasopressin injection and discussion on management of such patients.
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