???????? ??, ?????? ?, ????? ???, ?? ???????? ???, ???? ???, ?? ???? ?? ????? ????? ?
??????: ?? ????? ???????????? ??????, ????????????????? ???????? ????????????? ???? ??????? ???????? (WB MRI-DWIBS)?? ?????????-???????? ???? ???? ?????????? 123I-metaiodobenzylguanidine ???? [123I]-I-mIBG ????? ???? ???? ?????????? ?????????? ???????? ???? ??????????? ????? ????????? [123I]-I-mIBG ????? DWIBS ?? ????? ????????? ????????? ?????? ???????????????, ???????????, ???????????-???????, ????????????? ??????, ??? ????? ????? ????? ????????? ?????????? ??????, ????? ???????-???? ?????? ???????????? ???? ???? ????????????????. ?????? ????? ??????.
????????: 80 ?? [123I]-I-mIBG ????? DWIBS ???????? 31 ???? ??????? ???? 2009 ????? ???? 2019 ???? 30 ????????? ????? ??????????? ????? ??????? ???????????. 12 ???? ????????? NB ???? SIOPEN ????-????????????? ????????? ????????? ?????? ???? MIBG ???? ?????????????? ????? ????????? ?????? ??????? ????? ????????? ?????? WB MRI-DWIBS. ????? ????????? ????????-??? SPECT ??????????? ????????????? ????????? ???????????????? ???? ??????????????? ??????????????. ???? ?????? ???????????? ??????????? WB MRI-DWIBS ????? [123I]-I-mIBG ?????????? ????? ??????????, ???????????, ?????? ??????????, ??????? ????? ????? (PPV) ????? ???????? ????? ????? (NPV)?? ?????????????. [123I]-I-mIBG ????? DWIBS ?????? ???? ????? ?????????? ????? ???????? ???????????????.
???????: DWIBS ????? [123I]-I-mIBG ???????? 960 ?????????????? ????????? 890?? ???????????, ????? ??????? ???? ???? ??????? (??????=0.85 P <0.0001 ????? Chi 536.5975 P <0.0001). [123I]-I-mIBG?? ?????? ???????????? ???????????, WB MRI-DWIBS ?????? ?????????? 93%, ??????????? 78%, ?????????? 95%, PPV 77% ????? NPV 96%. ???????, ?????????? ????? ??????????, [123I]-I-mIBG ?????? ?????????? 93%; ??????????? 77%; ?????????? 97%; VPP 78%; VPN 95%, DWIBS?? ??????????. [123I]-I-mIBG ????? WB MRI-DWIBS SIOPEN ????????? ????????? ???? (Rho Spearman=0.88, P <0.0001).
???????: DWIBS ????? [123I]-I-mIBG ???????? ???? ?????? ??????????? ?????????: ? ???? ??????? SIOPEN ????????? ??????? ????? ????? ????????? ?????????????. WB MRI ???????? MIBG ????????? ????? ?????? ????? ???? ????????????????? ???????????. ?? ????? ???????????? ?????? ??????????? ???? ?????????? ???????? ?????????? ?????????????????.
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