జర్నల్ ఆఫ్ బయోడైవర్సిటీ, బయోప్రోస్పెక్టింగ్ అండ్ డెవలప్‌మెంట్

A lower incidence of bacterial vaginosis and urinary tract infections is linked to the presence and dominance of Lactobacillus in the vagina. The antiadhesion factors, by-products that are toxic to pathogens such hydrogen peroxide and bacteriocins, as well as possible immunological modulation or signalling effects, all appear to play a role in the mechanisms. GR-1, B-54, or RC-14 strains of Lactobacillus have been shown to improve the maintenance of a normal flora and lower the risk of urinary tract infections. Additionally, it has been demonstrated that ingesting these strains into the gut changes the vaginal flora to a healthier state. Furthermore, these strains have been proven in mice to colonise the gut, prevent the growth of intestinal and urogenital pathogens, and provide protection from infections. In vitro studies have shown lactobacilli to be able to prevent uropathogenic E. coli from growing and attaching to uroepithelial cells. Reduced infection rates in humans and animals are the result of this.

For the manufacture of biopharmaceuticals, vaccines, enzymes, plasma proteins, and antibodies, plants provide a reliable and affordable expression method. Recombinant protein production benefits from plants are appealing. Plant systems are more cost-effective because they may be manufactured on a greater scale than commercial techniques that use fermentation of bacteria, yeast, or expensively cultivated animal or human cell lines. When compared to bacterial and mammalian expression systems, the creation of recombinant proteins is risk-free and free of impurities. The risk of contamination by possible human pathogens is further reduced because plants do not serve as hosts for infectious diseases that affect humans. Plants are capable of post-translational changes that are similar to those found in naturally occurring systems. However, the expression levels are used in a commercial and economical way.