ఇంటర్నేషనల్ జర్నల్ ఆఫ్ న్యూరో రిహాబిలిటేషన్

Hypertension or high blood pressure is a prevalent and significant public health concern worldwide. Severe hypertension, defined as a systolic blood pressure are considered a medical emergency due to the increased risk of organ damage and cardiovascular events. While the association between hypertension and cerebrovascular disease is well-established, the prevalence of neurological complaints among patients presenting to the emergency department with severe hypertension remains an important area of investigation. This article aims to explore the prevalence of neurological complaints, including symptoms such as headache, visual disturbances, confusion, and focal neurological deficits, among ED patients with severe hypertension. Understanding the neurological manifestations of severe hypertension can help ED healthcare providers recognize and manage hypertensive emergencies promptly, leading to better patient outcomes and reduced morbidity.

Extracellular vesicles have emerged as a novel communication paradigm of the complement system in neurological diseases. Complement is an essential part of the innate immune system, playing a crucial role in host defense, tissue homeostasis, and immune regulation. However, dysregulation of the complement system has been implicated in the pathogenesis of various neurological disorders, including Alzheimer's disease, multiple sclerosis, and stroke. In recent years, it has become evident that complement components are present in EVs, which are small membranous vesicles secreted by cells into the extracellular space. These EV-associated complement proteins and microRNAs can modulate immune responses, contribute to neuroinflammation, and participate in the pathophysiology of neurological diseases. This article explores the role of EVs as a means of complement communication in neurological diseases and highlights their potential as diagnostic biomarkers and therapeutic targets.

Functional Neurological Disorder poses a significant challenge in the field of neurology. As a condition characterized by neurological symptoms without an underlying organic cause, FND requires specialized knowledge and skills to diagnose and manage effectively. Developing a comprehensive curriculum for FND within neurology education is crucial to ensure healthcare professionals are equipped to address this complex disorder. This article explores the importance of creating a curriculum dedicated to FND, discusses its key components, and highlights its potential impact on patient care.

Adverse neurological events, including stroke-like syndrome, are critical concerns in healthcare due to their potential impact on patient outcomes and quality of life. Understanding the incidence and clinical characteristics of these events is crucial for early recognition, accurate diagnosis and appropriate management. This article aims to provide a comprehensive review of the incidence rates and clinical features of adverse neurological events and stroke-like syndrome, shedding light on their presentation, underlying causes and implications for patient care. Adverse neurological events encompass a broad spectrum of conditions that can result in neurological dysfunction, ranging from transient symptoms to severe neurological deficits.