Xie Hongjian*, Shi Yujie ????? Kong Lingfei
??????? ???????? ?????????????? ??????? ??????? (NK)/T-???? ???????, ?????? ??? (PC-ENKTL), ????? NK ????? ???? ???????????? T ???? ????? ?????????? ????? ?????? ????, ??? ?????????-???? ????? (EBV) ????????? ?????? ????? ???????. ???? ?????? ???????? ???????????, PC-ENKTL ???????? ????????????????? ???????? ????????????????. ?????????????? ???? ??????? PC-ENKTL?? ?????????? ???? ?????????? ????????? ?????????? ???? ??????? ??????? ????????????????. ???? PC-ENKTL, ?????? ??????? ?????? ?? ??????, 38 ???? ?????? ?? ????????, ????????? ?????? ??????, ???????? ????? ????????? ???????????? ???? ??? ???? ???? ??????? ??????? ??????? ???????? ??????, ?????? ??? ?????? ?????????????. ?????, 1 cm ????? 6 cm ???? ???????? ???????. ???? ????? ????? ??? ????? ??????????? ??????????. ????????????, ?????????????????, ???????? ????? ????????? ???????? ??????? ???????? NK/T-???? ???????, ?????? ??? ?????????? ????????? ??????. ????????? ???? ???????? ??????????? ??????????? ???????? ????????? ????????????? ????? CD163, CD68, ???????????? ???? ???? (PD-1)/???????????? ???? ???? l ??????? 1(PD-L1) ????? ???????? 3 ??? ???????? ????? ????????????. ??????????? ?????? ????????? ???????? ?????????, ????? ???? ?????? ????????? ??????????? ????? ??????? ??????? 3 ??????? ?????????. ??????????????? ???????? NK/T-???? ????????? ??????????, ?????????????? ???? ??????? PC-ENKTL ?????? ??????? ????? ????????? ???? ??????? ????????????? ????? ???????? ???????. ????????? ???? ?????? ???? ????? ???????? ????????????? ???? ??????????????.
?????? ??????, ?????? ?????? ????? ?????? ??????????
???????: ??????? ???????? ????? ?????????? ??????????? 90 ???? ?????? ??????? ????????? ?????????, ?????? ??????? ???? ?????? ???-????? ????????? ???????. ??????????? ???????? ??????? ???? ????????? ???? ????????????? ??????? ????? ?????. ????????, ?????? ???? ?????? ?????? ????? ??????? ????? ???? ????????? ????????????? ?????????????? ? ??????? ???????????????.
????????: ?????????? 2016 ????? ?????? 2019 ???? ????????? ??????? ???????????????. ?????????? ????? ????? ????? ??????? ????? ??????? ??????? ????? ???? ????????? ????? ??????? ????? ?????????????.
???????: ?????? ???????? ??????? ????? ?????? ????????? 33·0%. ?????? (58·19%) ?????? ???? (41·8%) ???????? ??????? ???????? ????? ??????. 5 ????????? ???? ?????? ?????? ???? ???????? (27%) ???????? ????? ???????? (35%) ??????? ????? ???? ????????? ????????????. ??????? ?????? ?????????? 2016 (48·8%) ????? 2017 (41%)?? ?????????????. ??????? (40%) ????? ?????????? (39·52%) ???? ??????? ??????? ???? ???????????. ???? (45%) ????? ?????????? (40·6%) ????? ?????? ??????? ?????? ???????? ??????????????. ???????????? ???????? ?????? ????????? ??????? ????????????? ????? ???? (78.06%), ????? P. ?????????? ???? ???? (21·26 %). ?????? 70% ?????? ????? ???????? ????? ????? ?????????? ???????????? ????? ????? ??????????.
???????: ?????? ???????????? ????????? ?????????? ???????????????? ???????????? ???????? ?????? ?????????????. ??? ???????????, ???????? ???? ????? ???????? ???? ??????? ???????? ???????? ??????? ??????? ???? ??????????? ???? ?????.
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