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?????? ???????? ??????? ????? ?????? ??????????? ??????????? ?????? ???? ???? ????????? ?????????????? ????????????. ????? ????????? ???????? ????? ???? COVID-19?? ?????? ???? ???????? ????????????? ????????????? ?????? ??????? ????????????. ??????? ???????? ?????? ?????? ????? ?????????? miRNA ?? ???? ??? ?????? ?????????? ????? ???????? ????????????. ???????, ?????? ???????? ??????? ???????? miRNA ??? ?????? ?????????? ?????????, ??? COVID-19 ??????? ????????? ???????????? ????????????. ????????? ????? ????????? ?????? ?????????? ?????????, ????? ????????? ???????? ???? ?????? ??????? 3 ???? ???????? ?????? ??????????? (hsa-miR-486-5 p, hsa-miR-215-5 p, hsa-miR-941) mRNA ????????? ??????? ?????? ??????????. COVID-19 ???????. hsa-miR-215-5 p, hsa-miR-486-5 p ????? hsa-miR-941 ?????? 8, 93 ????? 99 ??????? ?????????????? mRNA??? ????????? ????????????? ????????????. COVID-19 ??????? ????? ????????? ???????? ??????? hsa-miR-486-5 p ??????????? ????? ???????? ???? ????? ?????????????? ???????? ???????????? ???????? ??????????. ????????, hsa-miR-486-5 p COVID-19 ???? ????? ????????? ????????? ??????????? ???????? ???????? ????? ???????? ?????????????.
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????????? T-???? ????????? (PTCL) ????? ?????? ????? ?????? ????????? ??????? ????? ???????????? ?????????? ????? ???????? ??????? ?????. ? ?????? ???????? PTCL ?????????? ?????????? ????? ?????? ?????????????? ??????????????. 2016 ???????????? ????? ?????? ???? ????, ????? ??????? ?????? ????? ?????? ???????? ?????? ??????? ???????????????. ? ??????? ????? ??????? ?????? ??????? ????? ?????????? ????? ????????????? ????? ??????? ???????? ????????? ??????????????? ?????? ????????? ???????, ?????????? ???????? ????? ????? ??????? ????????? ????? ???????? ???????????. PTCL ????? ?????????? ????????????? ?????? ????????? ??????? ????? ????????? ??????????, JAK-STAT ?????? ????? ????? ??????? ????????? ????? ???????? ?????????????????. ???????? ????????? ????? ????????????????? ??????? ????????? ????????? ????????? ???? ?????????? ???????. PTCL?? ???????? ??????? ???????? ?????????????? ?????-???? ????????? ????????? ????? ?????? ????? ??????? ??????? ???????????? ????? ?????, ASCT ??????? ??????? HSCT ???? ?????? ????? ???? ?????????? ????????? ????? ???????, HSCT?? ??? ????????? ?????????? ???? ???????? ???????? ????????? ???????????. , ????-???????????? ????? ?????????? ?????. PTCL?? ???????? ??????????????? ????? ?????? ???? ???????????? ????? ?????????.
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COVID-19 ?????????? ???????????????? ????? ?????? ????? ???????????????? ????? ?????? ????????. ??? ???? ????????????????? ?????? ????? ???????, ???????????? ???????, ???????? ?????? ???? ?????????? ?????? ????????? ???????. ? ???????? ????? ?????????? ?????? ??????? ?????????????, ????-???? ????? ???????????? ???????? ???????. ???? COVID-19 ?????? ?????????? ????? ????? ?????? ???????????? ?????? ????????????.
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COVID-19 ???????? ???????????????? 1 ???????? ???? ????????? ???????? ????? SARS-CoV-2 ????? ??????? ????????. COVID-19 ??????????? ?????? ????? ???????. ? ??????-??????? PRISMA-????????? ????????? ????????, ARDS, ???????? ????? DIC ??????????? ???????????? ???? ??? ??????????????? ???? ?????????? ????? ????????? ????? ????? ??? ???????? ???? ???? ?????????? ????????? ?????????????? ?????????????. ????????: ???? COVID-19?? ?????????? ??????? ??????????????? ???????? ???????? ?????????????? ???? ?????????? ???????????. ?????????? ??????? ??????? ????? ????????? ?????????? ?????????? ??????? ?????? ?????????????? ???? ????????? ???????? ????????? (ATA)?? ????????? ??????????? ????????? ??????. ????? ?????????? ??????????????? ???? ????????????? ????????? ?????? ???????? (VATA)?? ????? ????????? ??????. ?????? ???? ? ????? ??????? ??????????????? ??? ?????????? ????????? ???? ????????? ????????? ??????. ???????: ???? 10,523 ???? ??????? 56 ??????????, COVID-19 ????? ??????????????? ???????? (TBE??) ????? 586 ?????????????? ????????? 456 ???? ??????? ???????????. ????? ?????? ????? 1.3 TBE?? ???????. ??????? ????????? ??????????? ??? ?????? ????? ???????? ???????: ???????? ????? ?????????, ???????????? ?????????????, ??????????, ??????????? ????????? ????? ??????? ????????. ???? DVT??? ???? ???????????. ??? ????? ??????? ???????: ?????-????? ??????? ????????? ????? ???? ??????. 119 ???? ????? ?? ??????? ?????? DVT?? 26% ????? ???????? ????? ??????????? 79% ???? ???????? ???? ???????????, ??????????? ??????? ??????? ????? ???????? ???????? ?????? ????. ????????? ?????????? ?????? ????? ???????? ???? ???? ?????? 63 ????? 73. TE ?? ???? 91/150 ???? ??????? ????? ????????. ATA ?????, ???? COVID-19?? ????????? ??????? ????? 16 ????????? ???????????. VATA ?????, ???? ??????????? ???????? 34 ???????????? ??????????? ????? ????????? ????????, ??????? ????? ?????????????????? ????? ?????? ????? ????? ??????? ?????? ????? ??????. ????? ARDS, ???????? ????? DIC?? ????? ??????? ????????? ???????????. ????? ?? ??????? COVID-19 ????? ????????? ????? ????? ??????????? ?????????????? ????? ??????????? ????? ????? ????? ???????? COVID-19 ????? ????? ?????????? ??????????? ???? ?????????????. ???? ???????? ??????? ???????? ???? ?????????? ????????.