కాస్మోటాలజీ & ట్రైకాలజీ జర్నల్

Introduction: The eyebrow has a significant impact on the perceived beauty of the face, and in today’s culture women favour strong and healthy eyebrows. Although eyebrow transplantation and tattooing are two popular techniques for overcoming common concerns about weak and sparse hair growth, both techniques have disadvantages. Mesotherapy was developed in the 1950s, and was initially used to correct hair problems. The proven efficacy of hair mesotherapy has led to the use of the technique for eyebrow problems. Although there have been no published studies of eyebrow mesotherapy in the literature up till today, it is a minimal invasive and efficacious option available for patients.

Materials and Methods: A total of 12 patients with complaints of weak and sparse eyebrows (mean patient age: 32 (26–42) years) underwent eyebrow mesotherapy. Of the 12 patients, 8 were satisfied with the results on day 15 after treatment and clinically apparent thickening and darkening of colour was observed.

Discussion: Eyebrow mesotherapy provided good results in this study, which is at odds with the complications of the technique discussed in the literature. In brief, mesotherapy could be useful for correction of eyebrow problems that contribute to the perception of beauty. The results of this pilot study demonstrate that eyebrow mesotherapy is a minimal invasive method that may be tried prior to invasive and irreversible methods, such as eyebrow transplantation and tattooing.

Objective: Research shows that physical appearance is one of the key drivers of personal well-being. An improvement in facial attractiveness is associated with positive changes in emotional and social dimensions of one’s life. Hair colouring is an important means of cosmetic improvement in women and men. However, no research has been carried out so far to assess its impact on quality of life (QoL) using an instrument validated for cosmetic products and physical appearance. The main objective of this study was to assess the impact on QoL of two hair colouring products (Excellence® by L’Oréal Paris and Olia® by Garnier) using the BeautyQoL® questionnaire, specially designed and internationally validated for use in cosmetology.

Methods: A randomized control study has been carried out involving a total of 240 adult women (45-70 years old) assigned in two groups "Excellence" and "Olia". The BeautyQoL® questionnaire was administered in order to assess the impact of the two hair colouring treatments on QoL across five well-being dimensions: social life, self-confidence, mood, energy, and attractiveness. At the end of the study, subjective satisfaction questionnaires were used to assess the perceived performance and tolerability for each product, as well as interest in future use.

Results: The results of this study suggest that the QoL was improved in subjects using hair colouring products based on the overall and dimension-specific BeautyQoL® scores at the end of the experiment. The results of the satisfaction questionnaire were also conclusive, confirming the subjects’ good tolerability and overall satisfaction of the tested hair colouring products.

Conclusion: Hair colouring is used by millions of women and men who wish to look good, enhance their appearance, self-confidence and their overall attractiveness. For the first time, using the internationally validated BeautyQoL® questionnaire developed to specifically assess cosmetic products and physical appearance, the results of this study firmly establish that hair colouring contributes to improving the overall and dimension-specific QoL scores, and the well-being of users worldwide.

Background: Comedogenicity is an important consideration in development of topical products, such as cosmetics. An animal test using rabbit ear has long been served as a model for prediction of comedogenicity of topical products, but correlation to the human skin remained controversial. Isopropyl myristate and cocoa butter which are used as positive controls in animal test, also used in human clinical assay but report for the comedogenicity of those two positive controls in human, especially in Asian skin is limited.

Objective: To assess the comedogenicity of isopropyl myristate and cocoa butter in Asian skin using a modified human model established by Mill and Kligman.

Methods: We selected eight Asian subjects with prominent follicular orifices and the prone to acne type skin on the upper back. Two substances, isopropyl myristate and cocoa butter, were applied on the upper back skin three times a week for four weeks. Petrolatum and non-treated skin served as negative controls. Microcomedones were estimated by cyanoacrylate follicular biopsy at baseline and after four weeks of application. The number of follicles and microcomedones were determined by quantitative image analysis.

Results: Microcomedone activities of isopropyl myristate and cocoa butter have no significant difference to negative controls in Asian skin.

Conclusion: Comedogenic activity of isopropyl myristate and cocoa butter is too weak that those are not appropriate positive controls for clinical human assay in Asian skin. Further studies are necessary to determine appropriate positive controls in the human model for all ethnic populations.